The full manifest
200+ clinical reports, three raw file formats, updates for life.
Most consumer DNA tests give you one PDF and lock the data. A Dante Labs Genome Test gives you a portal full of clinical reports, three different raw file formats, and permanent report updates as new research is published. Here's everything that lands in your account.
Part 1 — The reports
200+ pre-built clinical modules.
The reports are the interpreted layer — the human-readable output that tells you what the raw variants mean. Dante groups them by clinical area, and each report has been built to a template so you can hand the PDF straight to a doctor without translation.
Cardiology
Coverage of the major cardiac risk genes — hypertrophic and dilated cardiomyopathy panels, long QT syndrome, familial hypercholesterolaemia (LDLR, APOB, PCSK9), Marfan syndrome, sudden cardiac death panels, and aortopathies.
Oncology and hereditary cancer
BRCA1 and BRCA2 hereditary breast and ovarian cancer analysis, Lynch syndrome (MLH1, MSH2, MSH6, PMS2, EPCAM), TP53 (Li-Fraumeni), PTEN (Cowden), APC (familial adenomatous polyposis), plus dozens of lower-frequency hereditary cancer genes on the ACMG SF v3.1 secondary-findings list.
Pharmacogenomics
How your genome metabolises common drugs. Covers CYP2D6, CYP2C19, CYP2C9, CYP3A4/5, VKORC1, TPMT, DPYD, SLCO1B1 and other enzymes relevant to warfarin, clopidogrel, SSRIs, tricyclics, opioids, statins, thiopurines and 5-fluorouracil.
Rare disease and carrier status
Screening for hundreds of monogenic rare disease genes plus recessive carrier status for common conditions like cystic fibrosis (CFTR), sickle cell (HBB), Tay-Sachs (HEXA), spinal muscular atrophy (SMN1), and fragile X (FMR1). Especially useful for prospective parents.
Neurology and dementia
APOE genotype and Alzheimer's risk, Parkinson's-linked genes (LRRK2, GBA, PARK7), Huntington's (HTT), spinocerebellar ataxias, and epilepsy panels.
Metabolic and wellness
Hemochromatosis (HFE), MTHFR variants, lactose persistence, caffeine metabolism, athletic performance markers (ACTN3, ACE), sleep chronotype and dozens of nutrigenomic markers. This is the section your friends will ask about; the cardiology section is the section your doctor will ask about.
Report modules are added over time. A test you buy in 2026 keeps receiving new report unlocks for years as Dante publishes them, at no additional charge.
Part 2 — The raw data
FASTQ, BAM and VCF — the "Holy Trinity".
The single most valuable thing Dante gives you is the raw files. Most consumer providers either don't offer this or charge extra. Dante bundles all three formats at no additional cost, and they're yours forever the moment your account is provisioned.
Why all three formats matter
FASTQ is the unaligned read data straight off the sequencer. If a new reference genome is published in five years, or you want to re-analyse with a different alignment algorithm, you can re-run the pipeline from FASTQ without paying anyone to re-sequence your saliva.
BAM is the aligned version — the same reads mapped to their positions on the reference genome. This is what most downstream analysis tools consume. It's compressed but random-access, so tools can jump to a specific gene without scanning the whole file.
VCF is the compact summary: just the positions where your sequence differs from the reference, plus quality scores. About 5 million lines per person. This is the file you'd feed into third-party interpretation tools like Promethease, SelfDecode, or Genetic Genie for additional reports beyond what Dante ships.
Part 3 — The portal
Genome Manager — lifetime access.
Everything lives in Dante's Genome Manager web portal. HIPAA and GDPR compliant, two-factor auth, standard encryption at rest and in transit. Reports render in the browser with variant details, ACMG classifications, references to the underlying literature, and a printable PDF for each module.
The download links for FASTQ, BAM and VCF are signed URLs generated on demand. Download them once locally and you own the files independent of Dante — no ongoing account required to keep the data. This matters given the company's April 2026 acquisition by Bio Cell Tech and the corporate reshuffling that followed.
Order once, own the data forever.
Save 10% with code GENOME. Free global shipping.
One more thing
Downloading the raw files: do it early, do it once.
The moment your Genome Manager account shows the files as ready, download all three. The FASTQ file is the big one (~350 GB) and slow browsers can struggle with it — use a download manager or a command-line tool like wget or curl for reliability. Corporate ownership at Dante changed in April 2026 and portals occasionally get reworked; your own local copy of FASTQ, BAM and VCF is the durable version of your genome.